Immunohistochemistry in Breast Pathology - Part 2a -
Malignant and benign tubular proliferations
Further example of a tricky tubular carcinoma and the use of myoepithelal markers to confirm invasive malignancy:
Further images showing the value of myoepithelial markers in confirming a diagnosis of nipple adenoma.
Low power view of P63 stain showing intact myoepithelial layer throughout lesion
Medium power view of CK5/6 stain in nipple adenoma - variable but convincing positive staining
High power view of CK 5/6 stain in nipple adenoma (florid papillomatosis)