Image of the Month (2010-3)
Metaplastic breast cancer with heterologous (rhabdomyoblastic) differentiation
Large breast tumour in an elderly female. Sections showed that it was composed almost
entirely of these strap-like rhabdomyoblastic spindle cells. These cells showed weak positive staining for the myoglobin immunostain.
A small focus of epithelial differentiation was seen in a section from only one of twelve tumour blocks examined.
Diagnosis - metaplastic carcinoma
Further view of spindle cell area
Further high power view of spindle cell area.