Image of the Month (2010-7)
Investigation of microcalcification
Screen-detected microcalcification in a 50 year old female
The following images show a series of levels through a block from a breast core biopsy taken at the screening
clinic to investigate microcalcification. Only a single calc was retrieved (see x ray below) and the first 6 levels showed
normal breast tissue only but then a duct starts to appear which by Level 8 shows a calc and surrounding inflammation and fibrosis
- these features are commonly seen in ducts containing high grade DCIS. As the levels deepen the DCIS becomes clear.
Core biopsy specimen X ray showing single focus of microcalcification
Level 6 showing duct - 'Mouse over' - Level 8 shows first view of calc and surrounding periductal inflammation/fibrosis.
Level 10 showing first sign of DCIS and comedo necrosis - 'mouse-over' for detail.
Level 12 showing unequivocal DCIS - 'mouse-over' for detail.