Image of the Quarter (2013-1)
High grade DCIS arising in an area of columnar cell change
50 year old woman - screen-detected microcalcs - excision biopsy. 'Mouse-over' for closer view.
The duct(s) show an early micropapillary architecture and columnar cell cyto-morphology.
These closer views show high grade malignant nuclear features: pleomorphism, chromatin clumping and prominent nucleoli. 'Mouse-over' for closer view.
This adjacent duct also shows features of high grade DCIS but with apocrine features.