Image of the Quarter (2014-1)
A good example of low grade DCIS
50 year old woman - small screen-detected distortion of architecture - core biopsy.
The core shows low grade DCIS. 'Mouse-over' for closer view. Main features: very uniform single cell population; small round nuclei; minimal atypia, no mitoses, no comedo necrosis.
The scale bar (top left) shows that the duct measures approximately 1mm in diameter.
These closer view shows further illustrate the homogeneity of this low grade cell population. 'Mouse-over' for closer view.
These views are of a CK14 immunostain showing a positive basal layer around the periphery of the duct and an absence of myoepithelial cells in the proliferating population - supporting a diagnosis of DCIS. 'Mouse-over' for further detail.