HOME PAGE PRACTICE & PROTOCOLS INVESTIGATIONS BENIGN / BORDERLINE MALIGNANT CASE MATERIAL

Image of the Quarter (2015-5)



A good example of a Juvenile fibroadenoma



13 year old female - large (3 cm) clinically benign lump left breast.




The tumour shows a low power pattern of a biphasic lesion with a rounded interface with surrounding fat, evenly spaced glands, and a cellular stroma. The 'Mouse-over' shows epithelial hyperplasia and stromal cellularity.

Juvenile fibroadenoma - evenly spaced glands and stroma and a rounded interface with the stroma



These further H&Es show show two patterns of stromal cellularity: Image A shows a more open pattern (mitoses were not easy to find in these areas); Image B (Mouse over) shows a more storiform pattern where mitoses could be found relatively easily.

Juvenile fibroadenoma - patterns of stromal cellularity


The final pair of views show stromal hypercellularity (storiform pattern - type B above) with focal stromal mitoses (Mouse-over).

Juvenile fibroadenoma - stromal mitoses





In this case stromal mitoses were quite patchily distributed with areas depicted in image A (see above) lacking mitoses and the more storiform areas showing mitotic activity.<


See also Fibroadenoma Variants.


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